Casasco d'Intelvi is a mountain village with 464 inhabitants located at a height of 822 meters. This area was already inhabited at the time of the Neolithic: the “cupelliformi” erratic boulders found in this territory testify precisely the presence of human settlements. Traces of the Ligurian period remain instead in the name of the village as, in the language of this ancient population, words ending in “asco” were very frequent. In 1335 it was part of Pieve d'Intelvi, while later it passed into the hands of various feudal families of the area; finally, it became part of the province of Como and the current name of "Casasco d'Intelvi" dates back to 1863.

Since 1° january 2018 it has become an hamlet of the municipality of Centro Valle Intelvi with Castiglione and San Fedele Intelvi.